Research Projects
H2IOSC is a pioneering project to create a collaborative cluster of European distributed research infrastructures involved in the humanities and cultural heritage sectors with operating nodes across Italy.
H2IOSC has been funded by the European Union Next Generation EU and the Italian Ministry of University and Research as part of the National Recovery and Resilience Plan (NRRP), with a partnership of 12 research Institutes from the National Research Council of Italy (CNR) and 18 operating units from the CNR’s Department of Social Science and Humanities, cultural heritage (CNR DSU).
WP3 -- Digital Resources Standardization, Consolidation & Alignment
The WP is devoted to the consolidation and overall alignment of both RIs and priority resources (cfr. WP2 Landscaping). On the basis of the outcomes of WP2 this workgroup will work towards: 1) filling the gaps found within each infrastructure, to reach the maturity threshold set by the project as entry point and, 2) align the participating infrastructures to reduce the lack of interoperability, encompassing different layers, including but not limited to: technological, ICT, and scientific issues.
ERA4TB project is a public-private initiative devoted to accelerate the development of new treatment regimens for tuberculosis.
It is expected to revolutionize the way in which tuberculosis treatments are developed thanks to its parallelized, multi-entry pipeline structure, analogue to a production line. This structure will enable to systematically investigate the efficacy of several drug candidates and combinations simultaneously while allowing new molecules to enter the project pipeline at the research stage corresponding to the degree of knowledge on said candidate drugs gathered before the project. With this approach, the ERA4TB consortium expects to reduce the time required for the development of new tuberculosis treatment regimens by up to a quarter.
The ERA4TB initiative integrates more than thirty organizations from the European Union and the United States among which are the main global actors in the fight against tuberculosis infection. ERA4TB has started in 2020 and will last six years, at the end of which, the consortium expects to have developed at least two or more new combination regimens with treatment-shortening potential ready for Phase II clinical evaluation. The partners intend to maintain the ERA4TB platform active beyond the project official duration.